Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice

HIGHLIGHTS

• who: Nathalie Hennuyer from the Recherche Medicale, Nuclear Receptors, Cardiovascular Diseases and Diabetes, European Genomic Institute for Diabetes, Lille, France, BenMay Institute for Cancer Research, The University of Chicago, Chicago, Illinois, USA. , Institut National de la Sante et de la Recherche Medicale, Unité have published the paper: Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 23/09/2015
• what: The authors report the development of a potent catalytic_site inhibitor suitable for in_vivo administration, and the characterization of its short . . .
  

   

  

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