Catching a spy: using the spycatcher-spytag and related systems for labeling and localizing bacterial proteins

HIGHLIGHTS

  • who: Daniel Hatlem and colleagues from the Cell Surface Group, Section for Evolution and Genetics, Department of Biosciences, University of Oslo have published the paper: Catching a SPY: Using the SpyCatcher-SpyTag and Related Systems for Labeling and Localizing Bacterial Proteins, in the Journal: (JOURNAL)
  • what: This work demonstrated how various recombinant antigens can be coupled to the OMV surface using the SpyCatcher system. Much effort has been put into designing VLP-antigen fusions; however, this approach has proven to be labor-intensive and time-consuming, since the fusions often misalign, or are unable to . . .

     

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