HIGHLIGHTS
- who: JNCI Cancer Spectrum ( and colleagues from the (UNIVERSITY) have published the Article: Cathepsin D Expression and Gemcitabine Resistance in Pancreatic Cancer, in the Journal: (JOURNAL)
SUMMARY
Background: Cathepsin-D (CatD), owing to its dual role as a proteolytic enzyme and as a ligand, has been implicated in cancer progression. The role of CatD in pancreatic ductal adenocarcinoma is unknown. Methods: CatD expression quantified by immunohistochemistry of tumor-tissue microarrays of 403 resected pancreatic cancer patients from the ESPAC-Tplus trial, a translational study within the ESPAC (European Study Group for Pancreatic Cancer . . .
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