Cation-chloride cotransporters kcc2 and nkcc1 as therapeutic targets in neurological and neuropsychiatric disorders

HIGHLIGHTS

  • who: Patricia Lam and collaborators from the Centre for Brain Research, Department of Anatomy and Medical Imaging, Faculty of Medical and Health, University of Auckland, Auckland, New Zealand have published the article: Cation-Chloride Cotransporters KCC2 and NKCC1 as Therapeutic Targets in Neurological and Neuropsychiatric Disorders, in the Journal: Molecules 2023, 28, 1344. of /2023/
  • what: The study broadly focused on KCCs with particular emphasis on KCC3, which is also abundantly expressed outside the CNS.
  • how: The long-term treatment of bumetanide was tested in a clinical trial in children with autism or . . .

     

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