Causal validation of the relationship between 35 blood and urine biomarkers and hyperthyroidism: a bidirectional mendelian randomization study and meta-analysis

HIGHLIGHTS

• What: Elevated total triiodothyronine (total Frontiers in Endocrinology frontiersin.org 10.3389/fendo.2024.1430798 SNP selection and consideration of confounding variables exist, this approach provides essential clues for understanding disease occurrence and treatment . Through this study, the authors aim to uncover the potential links between blood and urine biomarkers and the risk of hyperthyroidism, providing new insights and clues for the early diagnosis and treatment of hyperthyroidism. By identifying genetic variants (SNPs) associated with the trait of interest and using these SNPs as instrumental variables, randomized experiments can be simulated to assess the causal effects of . . .
  

   

  

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