Causes upregulation of long pentraxin-3 in the central nervous system of krabbe patients and mice

HIGHLIGHTS

• who: Daniela Coltrini and colleagues from the Department of Molecular and Translational Medicine, School of Medicine, University of Brescia, Brescia, Italy have published the research: Causes Upregulation of Long Pentraxin-3 in the Central Nervous System of Krabbe Patients and Mice, in the Journal: (JOURNAL)
• what: In all of the experiments, littermate wild_type (Galcwt) and homozygous (Galctwi/twi) animals were used.
• future: Studies will 12 of 17 be required to assess whether longitudinal blood measurement of PTX3 levels may represent a novel biomarker more sensitive than psychosine to predict onset after newborn screening . . .
  

   

  

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