Caveolae in rabbit ventricular myocytes: distribution and dynamic diminution after cell isolation

HIGHLIGHTS

  • who: Rebecca A.B. Burton from the Department of Pharmacology, University of Oxford, Oxford, United Kingdom have published the paper: Caveolae in Rabbit Ventricular Myocytes: Distribution and Dynamic Diminution after Cell Isolation, in the Journal: (JOURNAL)
  • what: The authors report significant changes in surface-sarcolemmal caveolae distribution within hours of cell isolation, with reductions in surfacesarcolemmal caveolae numbers by one-third within 3 h, and down to half by 8 h. The profound effect of a 75% reduction of caveolae on cardiac myocyte function suggests that the 50% loss of caveolae the authors report here . . .

     

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