Cbp is required for establishing adaptive gene programs in the adult mouse brain

HIGHLIGHTS

  • who: CBP et al. from the MLipinskiu2019s address: Department of Stem Cell and Regenerative Biology, Harvard University, Instituto de Investigaciu00f3n Sanitaria y Biomu00e9dica de Alicante (ISABIAL), Alicante, Spain have published the research: CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain, in the Journal: (JOURNAL) of October/19,/2022
  • what: Using this approach, the authors showed that the ablation of CBP in forebrain excitatory neurons in adult animals compromised their plasticity capabilities, particularly affecting behavioral tasks that rely on spontaneous exploratory behavior, such as novel object recognition and social recognition memory . . .

     

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