HIGHLIGHTS
SUMMARY
Aging and the activation of the rennin-angiotensin system play an important role in pathological cardiac remodeling (Driver et_al, 2008; Tang et_al, 2017). Early research has established that C-C motif chemokine ligand 17 (CCL17) plays an important role in T_cell development in the thymus, and it binds to C-C chemokine receptor 4 (CCR4) and displays chemotactic activity for T lymphocytes (predominantly T helper 2 - subtype cells); thus, it is also typically referred to as the thymus and activation-regulated chemokine (TARC; Imai et_al, 1996). The authors (Ye et_al, 2017; Ye et_al, 2015 . . .
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