Ccl5-producing migratory dendritic cells guide ccr5 monocytes into the draining lymph nodes

HIGHLIGHTS

  • who: BRIEF DEFINITIVE REPORT et al. from the Rockefeller University Press JExp. Med. , Vol. , No. , e, have published the research work: CCL5-producing migratory dendritic cells guide CCR5 monocytes into the draining lymph nodes, in the Journal: (JOURNAL) of 20/04/2023
  • what: Using labeling techniques and mixed bone marrow (BM) chimeras, the authors demonstrate that monocytes enter lymphatics in a cell-intrinsic CCR5-dependent manner, dependent on a CCR7driven migration of cDCs that produce the monocytic chemokine CCL5. The authors show that the true potential of monocytes as APCs is only revealed in the . . .

     

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