HIGHLIGHTS
- who: Yuanke Liang from the Department of Medical Oncology, University of, The Netherlands have published the article: CD146 increases stemness and aggressiveness in glioblastoma and activates YAP signaling, in the Journal: (JOURNAL)
- what: The authors examined the involvement of the cell adhesion molecule CD146/MCAM in regulating aggressiveness. The authors show that CD146 enhances multiple aggressive features of GBM, such as stemness, mesenchymal and invasive properties, and radioresistance. CD146 expression in glioma patients and in GBM cells To determine the expression of CD146 in GBM, the authors conducted an analysis of the GBM TCGA database . . .
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