Cd147 mediates epidermal malignant transformation through the rsk2/ap-1 pathway

HIGHLIGHTS

• who: Xu Zhang from the Department of Dermatology, Xiangya Hospital, Central South University have published the research work: CD147 mediates epidermal malignant transformation through the RSK2/AP-1 pathway, in the Journal: (JOURNAL)
• what: The authors treated DMBA/TPA-induced skin tumor mice model with CX-F9 to investigate the therapeutic potential of RSK2 in cSCC. With this study, the authors demonstrate for the first time that CD147 promotes the malignant transformation of keratinocytes and the tumorigenesis of skin cancers.
• how: All PCR primers used in this study are as follows ELISA was . . .
  

   

  

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