Cd27-igd- memory b cells are modulated by in vivo interleukin-6 receptor (il-6r) blockade in rheumatoid arthritis

HIGHLIGHTS

  • who: Zafar Mahmood from the (UNIVERSITY) have published the Article: CD27-IgD- memory B cells are modulated by in vivo interleukin-6 receptor (IL-6R) blockade in rheumatoid arthritis, in the Journal: (JOURNAL)
  • what: The authors demonstrate a significantly higher population of CD27-IgD- DN B cells in RA patients.
  • future: Future experiments need to address how peripheral IgA+ DN B cells may be related to the mucosal immune system. This may allow future studies to exploit DN B cells as biomarkers for response to TCZ.

SUMMARY

    Phenotypic analysis . . .

     

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