HIGHLIGHTS
- who: Luca Julius Pape and colleagues from the Pasteur Institute of Iran, Iran Shanghai Jiao Tong University, China have published the paper: CD38-specific nanobodies allow in vivo imaging of multiple myeloma under daratumumab therapy, in the Journal: (JOURNAL)
- what: The authors show that JK36 also detects CD38-expressing tumor cells with greater sensitivity pretreated mice resulted in weaker staining, possibly reflecting downregulation of CD38 due to therapeutic effects of daratumumab and JK36-hcAb in_vivo during the 24 hours of pretreatment and six hours imaging period. The study demonstrates that a nanobody recognizing a distinct . . .
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