Cd40-signalling abrogates induction of rorγt+ treg cells by intestinal cd103+ dcs and causes fatal colitis

HIGHLIGHTS

  • who: Christian Barthels from the Institute for Immunology, LMU Munich, Gro haderner Strasse, Planegg-Martinsried, Germany, Center of Allergy Environment (ZAUM), Helmholtz Germany. , Department of Medical Biochemistry, AMC, Amsterdam AZ, The Netherlands. , Department of Life Sciences and Biotechnology, University have published the article: CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 28/07/2016
  • what: The authors show CD40-signalling as a microbeindependent signal that can induce migration of CD103 - DCs from the lamina propria (LP) to the . . .

     

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