Cd44 contributes to the regulation of mdr1 protein and doxorubicin chemoresistance in osteosarcoma

HIGHLIGHTS

• who: Monserrat Gerardo-Ramírez and collaborators from the Department of Medicine I, University Medical Center of the Johannes Gutenberg University, Faculty of Biological Sciences, Friedrich-Schiller University, Jena, Germany have published the article: CD44 Contributes to the Regulation of MDR1 Protein and Doxorubicin Chemoresistance in Osteosarcoma, in the Journal: (JOURNAL) of 17/06/2022
• what: Drug resistance is one of the main reasons leading to treatment failure and poor prognosis. The authors showed that doxorubicin treatment leads to accumulation of p53 in Cd44-negative osteosarcoma cells .
• how: The authors investigated the role . . .
  

   

  

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