Cd44v3 is a marker of invasive cancer stem cells driving metastasis in gastric carcinoma

HIGHLIGHTS

  • who: Julie Giraud from the University of Bordeaux, rue Leo Saignat, Bordeaux, France have published the research: CD44v3 is a marker of invasive cancer stem cells driving metastasis in gastric carcinoma, in the Journal: (JOURNAL)
  • what: The authors characterized CD44 variants expressed in GC and evaluated the tumorigenic and metastatic properties of CD44v3+ cells and their clinical significance in GC patients. The authors show that CD44v3 is not expressed in healthy gastric mucosa and appears progressively in pre-neoplastic lesions, reaching 3.9-17.2% expression in GC.
  • how: Detailed methods about gastric . . .

     

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