Cd8+ t cells from patients with narcolepsy and healthy controls recognize hypocretin neuron-specific antigens

HIGHLIGHTS

• who: Natasja Wulff Pedersen from the Technical University of Denmark, Kgs Lyngby, Denmark have published the article: CD8+ T cells from patients with narcolepsy and healthy controls recognize hypocretin neuron-specific antigens, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors present a comprehensive screening for CD8+ T-cell recognition of NT1-relevant proteins in peripheral blood mononuclear cells (PBMCs) from well-characterized hypocretin-deficient NT1 patients and healthy controls. A potential limitation in this study is the fact that patient samples were collected from 1 to 9 years after disease onset.
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