Cd8+ t_cell-dependent immunotherapy

HIGHLIGHTS

• who: A reengineered common chain et al. from the DepartmentUniversity of Missouri, USA Valo Health, Boston, Massachusetts, USA. have published the Article: CD8+ T_cell-dependent immunotherapy, in the Journal: (JOURNAL)
• what: The authors demonstrate that this likely unique signaling pattern was the direct result of high-affinity binding of OMCPmutIL-2 to the cell surface, which resulted in the formation of a membrane complex comprising NKG2D, the IL-2 receptor, as well as the TCR within a large lipid raft-like structure. All peptides used in the study were a gift from the University of . . .
  

   

  

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