Cd9, a potential leukemia stem cell marker, regulates drug resistance and leukemia development in acute myeloid leukemia

HIGHLIGHTS

  • who: Yongliang Liu from the Center of Biological Therapy, Southwest Hospital, Army Medical University, Chongqing, China have published the research: CD9, a potential leukemia stem cell marker, regulates drug resistance and leukemia development in acute myeloid leukemia, in the Journal: (JOURNAL)
  • what: The authors aimed to identify LSC-specific surface markers and uncover the underlying mechanism of AML LSCs. The authors focused on A2M not only because its expression level in CD9+ cells was high but also because activation of A2M signaling was reported to promote the proliferation and survival of cancer cells . The authors . . .

     

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