Cdcp1 expression is frequently increased in aggressive urothelial carcinoma and promotes urothelial tumor progression

HIGHLIGHTS

• who: Miriam Saponaro from the DepartmentUniversity Medical have published the article: CDCP1 expression is frequently increased in aggressive urothelial carcinoma and promotes urothelial tumor progression, in the Journal: Scientific Reports Scientific Reports
• what: To further assess the relevance of these findings in human UC, the authors aimed to perform CDCP1 knockout (KO) in CDCP1 expressing cells with the CRISPR/Cas9 method. In line with these results, the first part of the study demonstrated that CDCP1 is overexpressed in UC when compared to NAT and is associated with MIBC.
• how: Taken together these data . . .
  

   

  

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