Cdk4/6 inhibition triggers icam1-driven immune response and sensitizes lkb1 mutant lung cancer to immunotherapy

HIGHLIGHTS

  • who: Xue Bai from the Ethics statement The study protocol of mouse care and experiments was approved by the Animal Care and Use Committee of Southern Medical University (protocol #SMUL2022189)All animal studies complied with relevant ethical regulations for animal testing and research. have published the research: CDK4/6 inhibition triggers ICAM1-driven immune response and sensitizes LKB1 mutant lung cancer to immunotherapy, in the Journal: (JOURNAL) of 17/09/2021
  • what: Leveraging single cell RNA sequencing data, the authors demonstrate that trafficking and adhesion process of activated T_cells are defected in genetically engineered Kras . . .

     

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