Cdk8/19 inhibition plays an important role in pancreatic β-cell induction from human ipscs

HIGHLIGHTS

• who: Kensuke Sakuma from the The human iPSC line Ff-I14-s, was kindly provided by the Center for iPS Cell Research and Application (CiRA) at the Kyoto UniversityThe Ff-I14s, line was established as an HLA homozygous iPSC line in a previous study [19]. The use of the iPSC line was approved by the Ethical Review Committee of the Shonan Health Innovation Park (Fujisawa, Kanagawa, Japan) and Kyoto University (#CiRA18-27). Cells were cultured and maintained on dishes coated by iMatrix, (Nippi, Tokyo, Japan) in StemFit AK N (Ajinomoto, Tokyo, Japan) at , u00b0C in a humidified . . .
  

   

  

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