Cdnf interacts with er chaperones and requires upr sensors to promote neuronal survival

HIGHLIGHTS

  • who: Ave Eesmaa et al. from the Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland have published the research work: CDNF Interacts with ER Chaperones and Requires UPR Sensors to Promote Neuronal Survival, in the Journal: (JOURNAL) of 17/Nov/2020
  • what: The aim of this study was to investigate the mechanism of action of CDNF through analyzing the involvement of UPR signaling in its anti-apoptotic function. In line with this, the authors show that CDNF can rescue 6-OHDA-lesioned DA neurons in culture . The authors show, for the first in the . . .

     

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