Cdon suppresses vascular smooth muscle calcification via repression of the wnt/runx2 axis

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• who: Byeong-Yun Ahn from the Mice bearing the Cdon-floxed allele (Cdonf/f) were obtained from EUCOMM and maintained as previously described For Cdon deletion in vascular muscle cells, Cdonf/f mice were crossed with SM22a-Cre, mice, which express tmx-inducible Cre recombinase under the transcriptional control of the SM22a (Tagln, smooth muscle protein, alpha) promoter. SM22u03b1Cre, mice were obtained from Severance Integrative Research Institute for Cerebral and Cardiovascular Diseases (SIRIC, Yonsei University Health System, Seoul, S. Korea). For deletion of one of the exons of the Cdon gene in VSMCs, approximately, or, week-old . . .
  

   

  

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