Cedar: incorporating cell type hierarchy improves cell type-specific differential analyses in bulk omics data

HIGHLIGHTS

• who: Luxiao Chen from the Department of Biostatistics University, GA , Atlanta, USA have published the research: CeDAR: incorporating cell type hierarchy improves cell type-specific differential analyses in bulk omics data, in the Journal: (JOURNAL)
• what: Observation the authors develop a novel statistical named CeDAR to incorporate the cell type hierarchy in cell type-specific differential analyses of bulk data. In the sections below, the authors show results from different types of tree structures. This analysis showcases the flexibility of CeDAR. The model described below will be applied to all covariates of interest.
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