Cefotaxime exposure selects mutations within the ca-domain of envz which promote antibiotic resistance but repress biofilm formation in salmonella

HIGHLIGHTS

  • who: Eleftheria Trampari and colleagues from the Quadram Institute Bioscience, Norwich, United Kingdom Medical School, University of East Anglia, Norfolk, United Kingdom have published the paper: Cefotaxime Exposure Selects Mutations within the CA-Domain of envZ Which Promote Antibiotic Resistance but Repress Biofilm Formation in Salmonella, in the Journal: (JOURNAL) of 27/04/2022
  • what: The authors assessed how Salmonella evolves and adapts in response to cefotaxime exposure in two very different lifestyles: planktonic cultures and biofilms. The authors show how these changes result in altered porin expression and reduced drug accumulation while also incurring . . .

     

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