Celastrol and resveratrol modulate sirt genes expression and exert anticancer activity in colon cancer cells and cancer stem-like cells

HIGHLIGHTS

  • who: Helena Moreira et al. from the Department of Basic Medical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Wroclaw have published the research: Celastrol and Resveratrol Modulate SIRT Genes Expression and Exert Anticancer Activity in Colon Cancer Cells and Cancer Stem-like Cells, in the Journal: Cancers 2022, x of /2022/
  • what: In this study the anticancer activities of both compounds were investigated in metastatic colon cancer cells (LoVo cells) and cancer stem-like cells (LoVo/DX). The authors show that LoVo/Dx cells display significantly higher activities of MDR transporters as detected by the . . .

     

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