HIGHLIGHTS
- who: Junxuan Ma from the (UNIVERSITY) have published the research: Celecoxib alleviates nociceptor sensitization mediated by interleukin-1beta-primed annulus fibrosus cells, in the Journal: (JOURNAL)
- what: The study shows that cxb significantly decreased the secretion of PGE-2 in CM of IL-1u03b2-stimulated hAFCs. The study used cell samples from patients with Pfirrmann grades II-III, as the authors aimed to focus on mild degeneration, which could benefit from cxb therapy.
- how: The effect of cxb on hAFCs-mediated nerve sensitization was tested in a model in that hAFCs were stimulated . . .
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