Cell angiopoietin-2 expression by impairing shear stress- related ampk/foxo1 signaling

HIGHLIGHTS

• who: Glycocalyx heparan sulfate cleavage et al. from the DivisionUniversity of Birmingham, Birmingham, Alabama, USA have published the Article: cell angiopoietin-2 expression by impairing shear stress- related AMPK/FoxO1 signaling, in the Journal: (JOURNAL)
• what: The authors determined the temporal associations between plasma (HS) levels as a marker of EG erosion and plasma Ang-2 levels in children with sepsis and in mouse models of sepsis.
• future: Given that soluble fragments of the degraded EG have recently been shown to have important bioactivity these considerations are logical for future investigations.

 

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