Cell autonomous angiotensin ii signaling controls the pleiotropic functions of oncogenic k-ras

HIGHLIGHTS

• who: Daniela Volonte from the Daniela Volonte, Morgan Sedorovitz, Victoria ECespedes, Maria L. Beecher, and Ferruccio Galbiati* From the Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA Edited by Eric Fearon have published the article: Cell autonomous angiotensin II signaling controls the pleiotropic functions of oncogenic K-Ras, in the Journal: (JOURNAL) of July/10,/2020
• what: The authors show that AGT is then converted to angiotensin II (Ang II) in a cell-autonomous manner by cellular proteases. The authors show that blockade of the Ang II receptor . . .
  

   

  

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