Cell cycle-dependent phosphorylation of the dna polymerase epsilon subunit, dpb2, by the cdc28 cyclin-dependent protein kinase*

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  • who: Tapio Kesti from the (UNIVERSITY) have published the article: Cell Cycle-dependent Phosphorylation of the DNA Polymerase Epsilon Subunit, Dpb2, by the Cdc28 Cyclin-dependent Protein Kinase*, in the Journal: (JOURNAL) of January/25,/2004
  • what: The authors show that the budding yeast Dpb2 is phosphorylated in a cell cycle-dependent manner during late G1 phase. Using site-directed_mutagenesis, the authors show that Ser-144 is sufficient for the formation of the lower mobility form of Dpb2 in_vivo. Consistent with the analysis described above, Ser-144 appears to be the predominant phosphorylated residue in . . .

     

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