Cell-intrinsic aryl hydrocarbon receptor signalling is required for the resolution of injury-induced colonic stem cells

HIGHLIGHTS

  • who: Kathleen Shah from the Department University of have published the research work: Cell-intrinsic Aryl Hydrocarbon Receptor signalling is required for the resolution of injury-induced colonic stem cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: Most of the studies on AHR functions in the gut have focussed on immune cell types, where it is involved in the maintenance of innate lymphoid cells (ILC3) or intraepithelial lymphocytes13-15 as well as in expression of the cytokine IL-22 which plays an important role in barrier defence10,16-18. The authors investigated AHR dependent . . .

     

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