Cell surface levels of organellar na+/h+ exchanger isoform 6 are regulated by interaction with rack1*

HIGHLIGHTS

• who: Ryuichi Ohgaki from the Ryuichi Ohgaki, Naomi Fukura, Masafumi Matsushita, Keiji Mitsui, and Hiroshi Kanazawa, From the Department of Biological Science, Graduate School of Science, Osaka University, Machikaneyama, Toyonaka, Osaka, Japan In mammalian cells, four Naⴙ/Hⴙ exchangers (, NHE9) are localized to intracellular compartments, and , are predominantly localized to sorting and recycling endosomes, to the trans-Golgi network, and , to the mid-trans-Golgi stacks. The unique localization of NHEs may contribute to establishing organelle-specific pH values and ion homeostasis in cells. Mechanisms underlying the regulation and targeting of organellar NHEs are largely unknown. We . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.