Cell surface-tethered il-12 repolarizes the tumor immune microenvironment to enhance the efficacy of adoptive t cell therapy

HIGHLIGHTS

• who: Jones et al. from the wnloaded from https://wwwscience.org at Technical University of Denmark on May, have published the research work: Cell surface-tethered IL-12 repolarizes the tumor immune microenvironment to enhance the efficacy of adoptive T cell therapy, in the Journal: (JOURNAL) of 27/04/2022
• what: Cell-tethered IL-12 increases the activity of adoptively transferred T_cells in the tumor To evaluate the ability of cell tethering to focus IL-12 activity to the TME, the authors compared immune activity in tumor and nontumor tissues. Together, this study shows that . . .
  

   

  

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