Cell-type-specific translational control of spatial working memory by the cap-binding protein 4ehp

HIGHLIGHTS

  • who: Shane Wiebe from the Department of Biochemistry, McGill University, McIntyre Medical Canada have published the Article: Cell-type-specific translational control of spatial working memory by the cap-binding protein 4EHP, in the Journal: (JOURNAL)
  • what: The authors show that a third translational suppressor, 4EHP is required for WM in both excitatory and inhibitory neurons (Figs 3D and 5B).
  • how: Behavioral experiments were conducted in a soundproof room between 800 and 1600. Given that miRNAs have been shown to regulate the mTOR pathway activity in the brain the authors investigated the activity . . .

     

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