Cellular atp levels determine the stability of a nucleotide kinase

HIGHLIGHTS

  • who: Oliver Brylski and collaborators from the Institute of Physical and Theoretical Chemistry, TU Braunschweig, Braunschweig, Germany, Braunschweig Integrated Centre of Systems Biology (BRICS), Braunschweig, Germany, Institute of Physical Chemistry II, Ruhr University, Bochum, Germany have published the article: Cellular ATP Levels Determine the Stability of a Nucleotide Kinase, in the Journal: (JOURNAL)
  • what: The authors demonstrate that the APS kinase domain undergoes a protein-stability cycle that is coupled to the different ligand-bound states during its catalytic cycle and cellular ATP levels. The microscope setup as well as the fluorophore pair used in . . .

     

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