Cellular chondroitin sulfate and the mucin-like domain of viral glycoprotein c promote diffusion of herpes simplex virus 1 while heparan sulfate restricts mobility

HIGHLIGHTS

  • who: Yara Abidine and collaborators from the Department of Clinical Microbiology, Umeå University, Umeå have published the research work: Cellular Chondroitin Sulfate and the Mucin-like Domain of Viral Glycoprotein C Promote Diffusion of Herpes Simplex Virus 1 While Heparan Sulfate Restricts Mobility, in the Journal: Viruses 2022, 14, 1836. of 17/08/2022
  • what: This study reports that different GAGs can have competing influences in mediating diffusion on the cells used here: chondroitin sulfate (CS) enhances free diffusion but hinders virus attachment to cell surfaces while heparan sulfate (HS) promotes virus confinement and increases . . .

     

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