Cellular electrical impedance as a method to decipher ccr7 signalling and biased agonism

HIGHLIGHTS

  • who: Nathan Vanalken and colleagues from the Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation have published the research work: Cellular Electrical Impedance as a Method to Decipher CCR7 Signalling and Biased Agonism, in the Journal: (JOURNAL)
  • what: The authors evaluated an alternative methodology to study CCR7 Cellular electrical impedance (CEI) is a label-free technology which yields a readout that reflects an integrated cellular response to ligand stimulation. The authors investigated to what extent a CEI-based assay can capture the natural ligand bias previously described for human CCR7.
 

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