HIGHLIGHTS
- who: Aristidis Moustakas from the DepartmentUppsala University have published the research work: Cellular heterogeneity in pancreatic cancer: the different faces of gremlin action, in the Journal: (JOURNAL) of 21/07/2022
- future: Until then however further experiments are required regarding the exact identification of the source and target cells of Grem1 protein.
SUMMARY
Moustakas et_al expressing myCAFs are contributing to maintain the neighbouring glandular PDAC cells in their epithelial, differentiated state (Fig 1). The experimental results tell that knockout of Grem1 in PDAC cells leads to more de-differentiated tumours of . . .
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