HIGHLIGHTS
- who: Dmitry V. Chistyakov et al. from the Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow , have published the Article: Cellular Model of Endotoxin Tolerance in Astrocytes: Role of Interleukin and Oxylipins, in the Journal: (JOURNAL)
- how: Although the molecular mechanisms underlying endotoxin tolerance remain elusive some features are described for macrophages . For the analysis the authors used a model of primary rat cortical astrocytes exposed to a low-grade concentration of LPS (10 ng/mL for 48 h) followed by stimulation with a middle-grade concentration of LPS (100 ng/mL . . .
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