HIGHLIGHTS
- who: Roseli da S. Soares and collaborators from the Department of Pharmacology, Escola Paulista Medicina, Universidade Federal Su00e3o Paulo (UNIFESP) have published the paper: Cellular Model of Malignant Transformation of Primary Human Astrocytes Induced by Deadhesion/Readhesion Cycles, in the Journal: (JOURNAL)
- what: The sequential deadhesion/readhesion of primary human astrocytes resulted in the clonal expansion of astrocyte-derived GFAP-positive cells with malignant traits, including high proliferative and migratory rates-comparable to a human GBM cell line (U87MG)-in addition to clonogenic capability and anchorage-independent growth.
- how: In the present 11 . . .
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