HIGHLIGHTS
- who: Zhi-Dong Liu from the Chinese Academy of Sciences, Shanghai, China University of Chinese Academy of Sciences, Beijing, China have published the article: Cellular model of neuronal atrophy induced by DYNC1I1 deficiency reveals protective roles of RAS-RAF-MEK signaling, in the Journal: (JOURNAL)
- what: The authors show that the DYNC1I1 deficiency, a neuron-specific dynein intermediate chain, causes neuronal atrophy in primary hippocampal neurons. The authors demonstrate that RAS-RAF pathway activates protective autophagy in primary hippocampal neuron with DYNC1I1 knockdown (Fig 4), which is favorable for structural and functional integrity of neuron . . .
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