HIGHLIGHTS
- who: Yongtao Wang from the (UNIVERSITY) have published the research: Cellular nanomechanics derived from pattern-dependent focal adhesion and cytoskeleton to balance gene transfection of malignant osteosarcoma, in the Journal: (JOURNAL)
- what: The topographical morphology of malignant MG63 cells was controlled by designed micropatterns through photolithography to induce different FAs and cytoskeletal structures.
- how: The results indicated that transfection efficiency was improved with enlarging FA area and cell nanomechanics in micropatterned osteosarcoma. The results indicated that cells could well accommodate to small micropatterns (706 1256 and 2826 u03bcm2) instead of large micropatterns (5024 . . .
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