Central role of glucocorticoid receptors in alzheimer’s disease and depression

HIGHLIGHTS

  • who: Laurent Givalois from the in Alzheimer's Disease and Related Disorders (EiAlz), Montpellier, France, University of Montpellier, Montpellier, France have published the research: Central Role of Glucocorticoid Receptors in Alzheimer's Disease and Depression, in the Journal: (JOURNAL) of 11/06/2018
  • how: GR A POTENTIAL THERAPEUTIC TARGET Based on the above-mentioned observations in humans and in animal models suggesting a deregulation of GR functioning several strategies targeting directly GR were tested in AD and MDD and seem to have an important therapeutic potential (Bachmann et_al 2003 Caraci et_al 2010 Figure 2).
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