HIGHLIGHTS
- who: Xiaoqian Yan from the Capital University, China have published the research work: Central role of microglia in sepsis-associated encephalopathy: From mechanism to therapy, in the Journal: (JOURNAL)
- what: The authors focused on the function, phenotype, and phenotypic transformation of microglia.
SUMMARY
Neuroinflammatory processes involve damage to the blood-brain barrier, pathways of inflammatory mediators, and activation of microglias, which amplify this process by releasing more inflammatory factors. The authors summarized the effects of inhibiting microglial activation or toxic factors after activation to alleviate cognitive impairment in SAE in recent . . .
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