Central role of pd-l1 in cardioprotection resulting from p2y4 nucleotide receptor loss

HIGHLIGHTS

  • who: Michael Horckmans et al. from the Autonomous University of Madrid, Spain have published the article: Central role of PD-L1 in cardioprotection resulting from P2Y4 nucleotide receptor loss, in the Journal: (JOURNAL)
  • what: This study reveals that antiinflammatory M2c macrophage polarization is induced in the PAT of P2Y4 KO ischemic mice.
  • how: Use of anti-PD-L1 blocking antibody To evaluate the importance of PD-L1 effects in the model anti-PD-L1 blocking antibody (B7-H1 clone 10F.9G2) (BioXCell Lebanon NH USA) and its control IgG2bk antibody were used at . . .

     

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