Ceramide analog [18f]f-hpa-12 detects sphingolipid disbalance in the brain of alzheimer’s disease transgenic mice by functioning as a metabolic probe

HIGHLIGHTS

• who: Simone M. Crivelli from the DepartmentUniversity, Universiteitssingel, ER Maastricht, The Netherlands, have published the article: Ceramide analog [18F]F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer’s disease transgenic mice by functioning as a metabolic probe, in the Journal: Scientific Reports Scientific Reports
• how: Biodistribution data were analyzed using two-way ANOVAs with APOE genes and AD genes as independent factors the LSD post hoc test was used for multiple comparisons.

SUMMARY

To uncover sphingolipid metabolic differences between APOE3, APOE4, E3FAD, and E4FAD, the authors performed the . . .

 



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