Cereblon-recruiting protacs: will new drugs have to face old challenges?

HIGHLIGHTS

  • who: Marcin Cieu015blak and Marta Su0142owianek from the Department of Food Science, Faculty of Pharmacy, Medical University of Lodz, ulMuszynskiego, Lodz, Poland have published the research: Cereblon-Recruiting PROTACs: Will New Drugs Have to Face Old Challenges?, in the Journal: Pharmaceutics 2023, 812 of 20/02/2023
  • what: __SECTION__ 5. Conclusions.
  • how: 4 of 23 This article presents CRBN-recruiting PROTACs developed in the last few years and summarizes their biological activity.

SUMMARY

    The first PROTAC targeting the BRD2/3/4 proteins was described by Winter et_al dBET1 is . . .

     

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