Cerebral capillary oxygen diffusion: exploring the concept of intracapillary hemoglobin conformational changes

HIGHLIGHTS

  • What: The authors propose that the intracapillary transformation of hemoglobin from the relaxed (R) to the tense (T) quaternary conformational state driven by deoxygenation and an overload of negative allosteric effectors and characterized by a lower more hyperbolic dissociation curve mitigates the pressure difference across capillaries ensuring a homogeneous pericapillary distribution of
  • Who: Gurgen Harutyunyan from the (UNIVERSITY) have published the research: Cerebral capillary oxygen diffusion: exploring the concept of intracapillary hemoglobin conformational changes, in the Journal: (JOURNAL)

SUMMARY

    Unit (a cylinder) supplied by a single capillary. According to this model . . .

     

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